7.3 Genetic Mutations Practice/Review

Gene Mutations Please begin reviewing gene mutations by taking a look at both point and frameshift mutations. Match each example to a type of mutation. Substitution ACA GTT --> ACT GTT Deletion ACA GTT --> ACG TT Insertion ACA GTT --> ACA GAT T Using the original DNA sequence shown below, determine the type of mutation that has occurred with the new sequence. T A C A C C T T G G C G A C G A C T New Sequence Type of mutation T A C A T C T T G G C G A C G A C T Substitution T A C G A C C T T G G C G A C G A C T Insertion T A C A C C T T G G G A C G A C T Deletion Click on each type of mutation and choose the category to place it where it belongs. Gene Mutations missense silent non sense frameshift- insertion frameshift- deletion Chromosomal Mutation insertion deletion translocation inversion duplication nondisjunction Which of the following is NOT a Point Mutation Missense Non Sense Silent Translocation What is another name for a substitution mutation? point mutations chromosomal mutations frame shift mutations Insertion and Deletion mutations can also be called what? substitution frame shift nondisjunction Fill in the blanks using the following words below. Gene Mutations- type of mutations that cause a change in the gene sequenceInsertion - type of mutation that adds a nucleotide in the DNA sequenceDeletion - type of mutation that subtracts a nucleotide in the DNA sequenceMissense - type of mutation that only affects 1 amino acidSilent - type of mutation that changes the DNA sequence but does not affect the amino acidNonsense - type of mutation that codes for a STOP amino acidGamete - type of cell that can pass down mutated cells to offspring