3/4 B Genetic Mutations

Master genetic mutations! This worksheet covers types of gene and chromosomal mutations with practice problems.

1)Matching Match the term with the correct description. Chromosomal Mutation A change in the number or structure of a single chromosome or whole sets of chromosomes Nondisjunction Chromosomes that don't separate during meiosis Translocation Chromosome pieces are moved onto another chromosomes Inversion Chromosome segment is inserted in reverse order Duplication A segment of a chromosome is repeated Deletion Part of a chromosome is removed 2)Gene mutations Match each term to the correct description Insertion One or more nucleotides are added to a gene Frameshift mutation The addition or deletion of one or more nucleotides that changes the number of complete codons Point mutation A change in one nucleotide that does not change the number of complete codons or the amino acid Deletion One or more nucleotides are removed from the gene Substitution One nucleotide is switched for another 3)If the original DNA is ATAACGCCTATT, how many codons are there?Hint: A codon is 3 letters at a time. 3 4 5 12 4)For the DNA sequence above (ATAACGCCTATT), what is the mRNA sequence?UAUUGCGGAUAA 5)If the "G" was deleted in this DNA sequence: ATAACGCCTATT, what type of mutation would occur? Frame-shift Point mutation 6)For the scenario above, when the "G" is deleted, how many complete codons would there then be? (ATAACGCCTATT, "G" removed: ATAACCCTATT) 7)Using the following DNA sequence, determine the type of mutation that has occurred with the new sequence. TAC ACC TTG GCG ACG ACT New sequence Type of mutation TAC ATC TTG GCG ACG ACT Substitution TAC GAC CTT GGC GAC GAC T Insertion TAC ACC TTG GGA CGA CT Deletion