Lupus Erythematosus 1

Match the English - Russian equivalents. (Click on the orange circle on the lift side, then drag and drop to the corresponding orange circle on the right side). complications осложнения implicate вовлекать, задействовать susceptibility восприимчивость lupus волчанка bound связанный expose подвергать воздействию Fill in the gaps (by clicking on each gap and choosing an appropriate answer). Well usually the immune system protects the body’s tissues from invaders, but lupus is an autoimmune disease, which means that immune cells start attacking the very tissues they are supposed to protect.With lupus, essentially, any tissue or organ can be targeted. And just like a ton of other autoimmune diseases though, it’s not completely clear why it develops, and like most diseases, it’s the result of both genetics and the environment. Fill in the gaps (type) with the words from the box below. A person has susceptibility genes—genes that make him susceptible to getting lupus, and he’s exposed to UV radiation in sunlight, which we know is an environmental risk factor for lupus. Well, given enough UV rays, a thing like a sunburn, the cell’s DNA can become so badly damaged, that the cell undergoes programmed cell death, or apoptosis, and it dies. This produces all these little apoptotic bodies, and exposes the insides of the cell, including parts of the nucleus, like DNA, histones, and other proteins, to the rest of the body. Well, those susceptibility genes specifically have an effect on this person’s immune system such that their immune cells are more likely to think that these are foreign or antigens, and since they’re from the nucleus, we call them nuclear antigens and immune cells try to attack them. Sort given words into categories. Click on the word and choose the category. CVS (cardiovascular) vegetations blod clots endocarditis GUS (genito-urinary) abnormal amounts of urine glomerulonephritis CNS (nervous) seizure psychosis Match two sentence halves. if the joints get inflamed, patients may also develop arthritis, specifically two or more joints to meet the criteria. If the kidneys are affected, patients might develop renal disorders, like abnormal amounts of urine protein or diffuse proliferative glomerulonephritis, Lupus can also affect the serosa, which is like the outer membrane of an organ or tissue. Vegetations are essentially clumps of fibrin, a blood-clotting protein